KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRL
All Species:
35.76
Human Site:
S207
Identified Species:
98.33
UniProt:
P01236
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01236
NP_000939.1
227
25876
S207
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Chimpanzee
Pan troglodytes
XP_518264
227
25749
S207
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Rhesus Macaque
Macaca mulatta
P55151
227
25953
S207
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Dog
Lupus familis
XP_545363
259
29663
S239
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
P06879
226
25478
S206
I
R
C
L
R
R
D
S
H
K
V
D
N
F
L
Rat
Rattus norvegicus
P01237
226
25734
S206
I
R
C
L
R
R
D
S
H
K
V
D
N
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513988
227
25514
S207
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Chicken
Gallus gallus
P14676
229
25845
S209
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Frog
Xenopus laevis
NP_001086486
230
26141
S210
L
H
C
L
R
R
D
S
H
K
I
D
N
Y
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.8
70.6
N.A.
60.7
62.1
N.A.
71.8
67.6
59.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
99.5
80.6
N.A.
77.5
77.9
N.A.
86.3
81.6
77.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
73.3
80
N.A.
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
100
0
0
0
0
100
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
78
0
0
0
0
0
0
100
0
0
0
0
0
0
% H
% Ile:
23
0
0
0
0
0
0
0
0
0
78
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% K
% Leu:
78
0
0
100
0
0
0
0
0
0
0
0
0
0
100
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
23
0
0
100
100
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
89
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _